Wednesday, August 21, 2013

Cancer-Surgery Complications Rise While Death Risk Drops

[unable to retrieve full-text content]

Source: www.medicinenet.com --- Wednesday, August 21, 2013
Title: Cancer-Surgery Complications Rise While Death Risk Drops Category: Health News Created: 8/20/2013 9:35:00 AM Last Editorial Review: 8/20/2013 12:00:00 AM ...

Source: http://www.medicinenet.com/guide.asp?s=rss&a=172816&k=Cancer_General

northern lights sign of the times keystone pipeline purim acc tournament big ten tournament big east tournament 2012

Saturday, August 17, 2013

President Sata suspends Copperbelt top cop

President Michael Sata has suspended Copperbelt Police Commissioner Mary Tembo with immediate effect.
Mary-Tembo 66

This is according to a statement released by Home Affairs Minister Edgar Lungu.Ms Tembo is alleged to have received a Toyota corolla worth K15 000 from a named mining company for her personal use without declaring it to her superiors.

Mr. Lungu said in view of allegations of corruption levelled against Ms. Tembo,President Sata has with immediate effect suspended her from exercising the powers and functions of her office.

Mr. Lungu said Ms Tembo cannot continue carrying out her duties because the alleged act of converting a motor vehicle or indeed any property donated by well-wishers to personal use without declaring that property to superiors contradicts the code of ethics for the public service.

He said the code of ethics for the public service states that a public service employee shall not accept gifts, rewards or hospitality or receive benefits of any kind from any person or organisation which might compromise or reasonably be seen to compromise one?s personal judgment or integrity.

He said the matter has since been handed over to the Anti-Corruption Commission for investigations.

Mr. Lungu added that President Sata has re-deployed Lusaka Province commissioner, Ms Joyce Kasosa to act during the investigations.
ZANIS

spor film izle

Source: http://www.statehouse.gov.zm/en/president-sata-suspends-copperbelt-top-cop/

pat summitt real housewives of atlanta colton bo ryan the last waltz earth day activities mel gibson

Friday, August 16, 2013

Singapore's Kernel Oil denies involvement in Indonesia graft case

'
$("#util_Login").html(toBeAppendded);
$(".ldap_iframe").html("");
setCookie("ldap_rdtc","",-1);
} else {
var ldap_remember = getCookie("ldap_remember");
var ldap_rdtc = getCookie("ldap_rdtc");
if(ldap_remember == "enable") {
if (ldap_rdtc == 1) {
setCookie("ldap_remember","",-1);
setCookie("ldap_rdtc","",-1);
$("#util_Login").html('');
$("#util_Login").attr("id","util_Logout");
} else {
setCookie("ldap_rdtc",1,1);
window.top.location.href = 'http://www.businesstimes.com.sg/ldap/regen.php?goto=/breaking-news/singapore/singapores-kernel-oil-denies-involvement-indonesia-graft-case-20130815';
}
} else {
setCookie("ldap_rdtc","",-1);
$("#util_Login").html('');
$("#util_Login").attr("id","util_Logout");
}
}
},
complete:function(){},
error:function(xhr, status, error){
var ldap_remember = getCookie("ldap_remember");
var ldap_rdtc = getCookie("ldap_rdtc");
if(ldap_remember == "enable") {
if (ldap_rdtc == 1) {
setCookie("ldap_remember","",-1);
setCookie("ldap_rdtc","",-1);
$("#util_Login").html('');
$("#util_Login").attr("id","util_Logout");
} else {
setCookie("ldap_rdtc",1,1);
window.top.location.href = 'http://www.businesstimes.com.sg/ldap/regen.php?goto=/breaking-news/singapore/singapores-kernel-oil-denies-involvement-indonesia-graft-case-20130815';
}

} else {
setCookie("ldap_rdtc","",-1);
$("#util_Login").html('');
$("#util_Login").attr("id","util_Logout");
}
}
});

function getCookie(c_name) {
var i,x,y,ARRcookies=document.cookie.split(";");
for (i=0;i

Source: http://www.businesstimes.com.sg/breaking-news/singapore/singapores-kernel-oil-denies-involvement-indonesia-graft-case-20130815

zimmerman charged bonobos charles manson actuary elon musk fox mole manson

Sunday, June 23, 2013

NSA leaker charged with espionage, theft

This photo provided by The Guardian Newspaper in London shows Edward Snowden, who worked as a contract employee at the National Security Agency, in Hong Kong, Sunday, June 9, 2013. The man who told the world about the U.S. government?s gigantic data grab also talked a lot about himself. Mostly through his own words, a picture of Edward Snowden is emerging: fresh-faced computer whiz, high school and Army dropout, independent thinker, trustee of official secrets. And leaker on the lam. (AP Photo/The Guardian) MANDATORY CREDIT

This photo provided by The Guardian Newspaper in London shows Edward Snowden, who worked as a contract employee at the National Security Agency, in Hong Kong, Sunday, June 9, 2013. The man who told the world about the U.S. government?s gigantic data grab also talked a lot about himself. Mostly through his own words, a picture of Edward Snowden is emerging: fresh-faced computer whiz, high school and Army dropout, independent thinker, trustee of official secrets. And leaker on the lam. (AP Photo/The Guardian) MANDATORY CREDIT

(AP) ? The Justice Department has charged former National Security Agency contractor Edward Snowden with espionage and theft of government property in the NSA surveillance case.

Snowden, believed to be holed up in Hong Kong, has admitted providing information to the news media about two highly classified NSA surveillance programs.

A one-page criminal complaint unsealed Friday in federal court in Alexandria, Va., says Snowden engaged in unauthorized communication of national defense information and willful communication of classified communications intelligence information. Both are charges under the Espionage Act. Snowden also is charged with theft of government property. All three crimes carry a maximum 10-year prison penalty.

The federal court in the Eastern District of Virginia where the complaint was filed is headquarters for Snowden's former employer, government contractor Booz Allen Hamilton.

The complaint is dated June 14, five days after Snowden's name first surfaced as the leaker of information about the two programs in which the NSA gathered telephone and Internet records to ferret out terror plots.

The complaint is an integral part of the U.S. government's effort to have Snowden extradited from Hong Kong, a process that could turn into a prolonged legal battle. Snowden could contest extradition on grounds of political persecution. In general, the extradition agreement between the U.S. and Hong Kong excepts political offenses from the obligation to turn over a person.

Sen. Bill Nelson, D-Fla., a member of the Senate Armed Services Committee, welcomed the charges. "I've always thought this was a treasonous act," he said in a statement. "I hope Hong Kong's government will take him into custody and extradite him to the U.S."

Michael di Pretoro, a retired 30-year veteran with the FBI who served from 1990 to 1994 as the legal liaison officer at the American consulate in Hong Kong, said "relations between U.S. and Hong Kong law enforcement personnel are historically quite good."

"In my time, I felt the degree of cooperation was outstanding to the extent that I almost felt I was in an FBI field office," said di Pretoro.

The success or failure of any extradition proceeding depends on what the suspect is charged with under U.S. law and how it corresponds to Hong Kong law under the treaty. In order for Hong Kong officials to honor the extradition request, they have to have some applicable statute under their law that corresponds with a violation of U.S. law.

However, Snowden's appeal rights could drag out any extradition proceeding.

Disclosure of the criminal complaint came as President Barack Obama held his first meeting with a privacy and civil liberties board as his intelligence chief sought ways to help Americans understand more about sweeping government surveillance efforts exposed by Snowden.

The five members of the little-known Privacy and Civil Liberties Oversight Board met with Obama for an hour in the White House Situation Room, questioning the president on the two NSA programs that have stoked controversy.

One program collects billions of U.S. phone records. The second gathers audio, video, email, photographic and Internet search usage of foreign nationals overseas, and probably some Americans in the process, who use major providers such as Microsoft, Google, Apple, and Yahoo.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-06-21-NSA%20Surveillance/id-5a399e4670b34b789b09ee1bf63e24b4

tony nominations dark knight trailer dallas mavericks washington capitals delmon young amare stoudemire tallest building in the world

Saturday, June 22, 2013

Meet B, the flying car that'll make it even easier to terrorize local wildlife (video)

DNP Meet B, the flying car that'll make it even easier to terrorize local wildlife

Sometimes, when a remote-control car and a remote-control helicopter love each other very much, they come together and produce something like the B. Well, okay, that's not exactly how this small flying car came about, but it's a nice story. Witold Mielniczek, a computational engineering Ph.D. candidate at the University of Southampton, is currently running a Kickstarter for the simply named B, a hybrid car-helicopter that can handle both challenging terrains and limited air travel. Equipped with a sleek polycarbonate chassis, four propeller driving units (a fancy way of saying wheels) and an HD 1,280 x 720 camera to record one's travels, B seems to be the little flying car that could. In the greater scheme of things, Mielniczek hopes that B will one day be able to operate on water in addition to land and air. While it's no Avengers helicarrier, we suppose every journey begins with a single step. To see B in action, check out the video after the break.

Filed under:

Comments

Source: Kickstarter

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/qm9UzN5FOo0/

2012 ncaa tournament schedule laurent robinson dantoni leah remini black and tan dwight howard trade ncaa bracket 2012

Graphene-based system could lead to improved information processing

June 21, 2013 ? Researchers at MIT have proposed a new system that combines ferroelectric materials -- the kind often used for data storage -- with graphene, a two-dimensional form of carbon known for its exceptional electronic and mechanical properties. The resulting hybrid technology could eventually lead to computer and data-storage chips that pack more components in a given area and are faster and less power-hungry.

The new system works by controlling waves called surface plasmons. These waves are oscillations of electrons confined at interfaces between materials; in the new system the waves operate at terahertz frequencies. Such frequencies lie between those of far-infrared light and microwave radio transmissions, and are considered ideal for next-generation computing devices.

The findings were reported in a paper in Applied Physics Letters by associate professor of mechanical engineering Nicholas Fang, postdoc Dafei Jin and three others.

The system would provide a new way to construct interconnected devices that use light waves, such as fiber-optic cables and photonic chips, with electronic wires and devices. Currently, such interconnection points often form a bottleneck that slows the transfer of data and adds to the number of components needed.

The team's new system allows waves to be concentrated at much smaller length scales, which could lead to a tenfold gain in the density of components that could be placed in a given area of a chip, Fang says.

The team's initial proof-of-concept device uses a small piece of graphene sandwiched between two layers of the ferroelectric material to make simple, switchable plasmonic waveguides. This work used lithium niobate, but many other such materials could be used, the researchers say.

Light can be confined in these waveguides down to one part in a few hundreds of the free-space wavelength, Jin says, which represents an order-of-magnitude improvement over any comparable waveguide system. "This opens up exciting areas for transmitting and processing optical signals," he says.

Moreover, the work may provide a new way to read and write electronic data into ferroelectric memory devices at very high speed, the MIT researchers say.

Dimitri Basov, a professor of physics at the University of California at San Diego who was not connected with this research, says the MIT team "proposed a very interesting plasmonic structure, suitable for operation in the technologically significant [terahertz] range. ? I am confident that many research groups will try to implement these devices."

Basov cautions, however, "The key issue, as in all of plasmonics, is losses. Losses need to be thoroughly explored and understood."

In addition to Fang and Jin, the research was carried out by graduate student Anshuman Kumar, former postdoc Kin Hung Fung (now at Hong Kong Polytechnic University), and research scientist Jun Xu. It was supported by the National Science Foundation and the Air Force Office of Scientific Research.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/physics/~3/4eQl1-5Fu_M/130621095620.htm

avengers soa andy williams andy williams Lady Gaga New Girl Avalanna

Gillmor Gang Live 06.21.13. (TCTV)

Gillmor Gang test patternGillmor Gang Live - Robert Scoble, Kevin Marks, Keith Teare, and Steve Gillmor. Recording for today has concluded.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/w3K26l8OD8I/

school shootings Jenni Rivera Adam Lanza Facebook the hobbit mick jagger Newton Shooting Newtown Shooting

Watchdog faults background check of NSA leaker

WASHINGTON (AP) ? A government watchdog testified Thursday there may have been problems with a security clearance background check conducted on the 29-year-old federal contractor who disclosed previously secret National Security Agency programs for collecting phone records and Internet data ? just as news media disclosed more information about those programs.

Appearing at a Senate hearing, Patrick McFarland, the U.S. Office of Personnel Management's inspector general, said USIS, the company that conducted the background investigation of former NSA systems analyst Edward Snowden, is now under investigation itself.

McFarland declined to say what triggered the inquiry of USIS or whether the probe is related to Snowden. But when asked by Sen. Jon Tester, D-Mont., if there were any concerns about the USIS background check on Snowden, McFarland answered: "Yes, we do believe that there may be some problems."

Meanwhile, new details emerged about the scope of two recently disclosed NSA programs ? one that gathers U.S. phone records and another that is designed to track the use of U.S.-based Internet servers by foreigners with possible links to terrorism.

Two new documents published Thursday by The Guardian newspaper ? one labeled "top secret" and the other "secret" ? said NSA can keep copies of intercepted communications from or about U.S. citizens indefinitely if the material contains significant intelligence or evidence of crimes.

McFarland declined after the Senate hearing to describe to reporters the type of investigation his office is conducting. Sen. Claire McCaskill, D-Mo., said she was told the inquiry is a criminal investigation related "to USIS' systemic failure to adequately conduct investigations under its contract."

"We are limited in what we can say about this investigation because it is an ongoing criminal matter," said McCaskill, chairwoman of the Senate subcommittee on financial and contracting oversight. "But it is a reminder that background investigations can have real consequences for our national security."

McCaskill's panel conducted the hearing jointly with Tester's subcommittee on efficiency and effectiveness of federal programs.

USIS, based in Falls Church, Va., said in a statement that it has never been informed that it is under criminal investigation. USIS received a subpoena from the inspector general's office in January 2012 for records, the statement said. "USIS complied with that subpoena and has cooperated fully with the government's civil investigative efforts," according to the company.

USIS declined to comment on whether it conducted a background investigation of Snowden. The company said it performs thousands of background investigations each year for OPM and other government agencies. "These investigations are confidential and USIS does not comment on them," the USIS statement said.

The background check USIS performed on Snowden was done in 2011 and was part of periodic reinvestigations that are required for employees who hold security clearances, according to McFarland and Michelle Schmitz, the assistant inspector general for investigations at OPM.

Schmitz said the investigation of USIS commenced later in 2011.

Booz Allen Hamilton, the company where Snowden was working at the time of the disclosures, fired him for violations of the firm's code of ethics and firm policy. The company said he had been a Booz Allen employee for less than three months.

Snowden worked previously at the CIA and probably obtained his security clearance there. But like others who leave the government to join private contractors, he was able to keep his clearance after he left and began working for outside firms.

Of the 4.9 million people with clearance to access "confidential and secret" government information, 1.1 million, or 21 percent, work for outside contractors, according to a January report from the Office of the Director of National Intelligence. Of the 1.4 million who have the higher "top secret" access, 483,000, or 34 percent, work for contractors.

OPM's Federal Investigative Services division performs almost all the background investigations for federal agencies and nearly 75 percent of the investigators who perform background checks are contractors, according to information on the agency's website.

At the hearing, McFarland called for much closer oversight of the investigators who conduct background checks. He said that 18 background investigators and record searchers have been criminally convicted since 2006 for fabricating information in background reports.

McFarland's office is actively working on 11 fabrication cases and another 36 cases involving background investigators are pending, according to data he provided to the subcommittees.

Of the 18 investigators who were criminally convicted, 11 were federal employees and seven were contractors. Of the 47 active and pending cases, six involve federal employees and 41 involve contractors, according to McFarland.

The new documents revealed by The Guardian were signed by Attorney General Eric Holder. They include point-by-point directions on how an NSA employee must work to determine that a person being targeted has not entered the United States. If NSA finds the target has entered the U.S., it will stop gathering phone and Internet data immediately, the documents say.

If supervisors determine that information on a U.S. person or a target who entered the U.S. was intentionally targeted, that information is destroyed, according to the documents.

But if a foreign target has conversations with an American or a U.S.-based person whom NSA supervisors determine is related to terrorism, or contains significant intelligence or evidence of crimes, that call or email or text message can be kept indefinitely. Encrypted communications also can be kept indefinitely, according the documents.

Administration officials had said the U.S. phone records NSA gathered could only be kept for five years. A fact sheet those officials provided to reporters mentioned no exceptions.

The documents outline fairly broad authority when the NSA monitors a foreigner's communications. For instance, if the monitored foreigner has been criminally indicted in the U.S. and is speaking to legal counsel, NSA has to cease monitoring the call. The agency, however, can log the call and mine it later so long as conversation protected by attorney-client privilege is not used in legal proceedings against the foreigner.

The NSA had no comment when asked about the newly revealed documents.

___

Follow Lardner on Twitter at https://twitter.com/rplardner and Dozier on Twitter at http://twitter.com/kimberlydozier

Source: http://news.yahoo.com/watchdog-faults-background-check-nsa-leaker-235639806.html

bent new york jets etch a sketch romney sean payton saints bounty program toulouse france ny jets

Senators announce border security compromise

WASHINGTON (AP) ? Republican senators searching for compromise on an immigration bill have announced an amendment to dramatically increase agents, technology and fencing along the U.S.-Mexico border.

The deal was announced on the Senate floor Thursday afternoon by GOP Sens. John Hoeven of North Dakota and Bob Corker of Tennessee. It would double border patrol agents on the border, build 700 new miles of fencing and spend billions to deploy additional high-tech tools including drones, radar and seisimic monitoring.

Corker says it amounts to "investing resources to secure our border that have never been invested before."

Even before being formally introduced the amendment was adding powerful momentum to the White House-backed legislation, which looked likely to pass the Senate with a bipartisan majority in coming days.

Source: http://news.yahoo.com/senators-announce-border-security-compromise-182812632.html

bay bridge band of brothers presidents george washington horsetail falls ice t president day

Video Ad Buying Platform TubeMogul Hires Google Media Platforms Head Chip Scovic As CRO

Chip-Scovic-TubeMogulTubeMogul has come a long way since being founded in 2006. The company, which originally provided an analytics service for video distributors, moved into advertising a couple of years ago. With a platform that brand advertisers can use to systematically purchase online video inventory, it's gotten pretty big since then -- and it keeps getting bigger.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/rEKNQLOxJK4/

maya angelou joan of arc tony robbins bon iver abraham lincoln vampire hunter their eyes were watching god lara logan

Acer Aspire R7-571-6858


The Acer Aspire R7-571-6858 might be the first desktop replacement laptop for the all-in-one desktop generation. Featuring an adjustable easel-style stand/hinge combination, it's the first laptop I've seen with a fully adjustable monitor, and more closely resembles a desktop than a laptop, with a flipping, folding, floating display design that is certainly unique. While this new design will turn heads and may hint at the shape of things to come, the overall design is dragged down by the decision to swap the touchpad and keyboard, resulting in a design that is awkward at best.

Design
With so many ultrabooks on the market, it's refreshing to see a full-bodied desktop replacement in the labs. The Aspire R7 is by no means svelte, measuring 1.1 by 14.8 by 10.0 inches (HWD) and weighing 5.22 pounds. The construction blends lightweight plastic on the lid and chassis with a metal hinge.

The most prominent feature on the Aspire R7 is the unique combination hinge and display stand, which Acer calls the "Ezel" hinge. Much like the multi-mode Lenovo IdeaPad Yoga 13, the Aspire R7 uses the Ezel hinge to offer four different usage modes: Notebook Mode, Ezel Mode, Pad Mode, and Display Mode. In each mode, the 15.6-inch display flips and folds to present the 1,920-by-1,080 touch display at the most comfortable angle. As desk-bound systems go, it's one of the most comfortable implementations of touch that we've used.

Notebook mode is the closest of the four to a regular clamshell laptop, with the display lining up with the back edge of the laptop chassis. In this mode, it functions much like any other touchscreen-equipped laptop, aside from the unusual keyboard layout (more on that in a moment).

In Ezel mode, the display stand allows for a monitor-like setup much more like a desktop display. In addition to looking cool, this mode has the benefit of best utilizing the touch display, letting you bring the screen closer and put it at an angle more comfortable than a regular touch-enabled laptop screen. The Ezel hinge features two adjustable hinges, and both hold firmly enough that when touching and tapping the screen, there's no noticeable screen wobble. The unfortunate side-effect of the sturdy hinges, of course, is that they are just as stiff when adjusting the angle of the display and opening the closed laptop.

Folding the Ezel hinge flat with the screen out puts the laptop into Pad Mode, which converts the Aspire R7 into something like a tablet. It's too large to simply pick up and use on the go, though it can certainly be moved from one room to the next with relative ease. Though not exactly mobile, Pad mode does make for a more comfortable table-top touch experience, and the bulk of the hinge sets the display at an angle, more like a small All-in-One system laying nearly flat. Getting the Aspire R7 out of Pad mode is sometimes difficult, with the sturdy hinges requiring some force to pry the display up and manhandle it back into position.

Finally, the display can be tipped back and flipped over, to show the screen to someone on the opposite side. We've seen similar screen-sharing concepts on the Lenovo Yoga and the Asus Taichi 21, but the Aspire R7 doesn't do much to make this dubious concept seem more reasonable?showing someone else the display requires giving up your own, and it still seems like more trouble than looking at the same screen while standing side-by-side. As with the Asus Taichi, the display sharing feature feels more like an afterthought based on the fact that the stand allows flipping the screen, added to pad out the feature list.

The layout?keyboard on bottom, touchpad on top?is almost as weird as the bizarre easel/stand and display/monitor. While the reasoning is at least logical?with a floating touchscreen you don't necessarily need a touchpad, and the angle of the floating display would block part of the keyboard in normal use?there's no ignoring the fact that the switch is otherwise difficult to justify. The traditional keyboard and touchpad arrangement wasn't arbitrary; properly placed palm rests make typing more ergonomic and on-the-go laptop use easier, and a touchpad located below the spacebar lets you navigate without having to hover over the keyboard or worry about unintentional keystrokes. This new design eliminates those important touches, and just feels like change for the sake of change.

The Aspire R7 boasts four speakers for fuller sound, with Dolby Home Theater v4 adding to the overall quality. The sound quality was actually quite good, and the volume was impressive?loud enough to disturb the neighbors, and clear enough that you might want to. Flip the display from Ezel mode to Display also switches the right and left stereo channels, to match the right and left of the person viewing the screen.

Features
The Aspire R7 places all of its ports and connectors in the bottom half of the system. While this isn't uncommon for a laptop, the desktop-like design makes it feel more like an all-in-one placing all of the ports in the monitor stand, as is seen on the Vizio All-in-One systems.

On the right is a power button and volume controls, one USB 2.0 port with power for charging devices, an SD card slot (SD, SDHC, SDXC), and a Kensington lock slot for physically securing the device. On the left is a mini DisplayPort and full-size HDMI output for connecting an external monitor or TV, and two faster USB 3.0 ports. Despite the Aspire R7's undeniably desktop-like nature, you'll have to use the built-in 802.11n Wi-Fi for networking because there's no Ethernet port to plug into. Also, the Aspire R7 has built-in Bluetooth 4.0, with support for stereo sound, as well as an integrated 720p webcam above the screen.

Though the Aspire R7 is pretty big, the storage is a bit on the small side, with a 500GB spinning hard drive paired with a 24GB solid-state drive (SSD) for snappy performance.

Acer loads up the Aspire R7 with a lot of media and social apps, like Zinio and Next Issue magazine readers, Ebay and Amazon for shopping, and an array of others, like iCookbook, Spotify, ChaCha, Netflix, HuluPlus, and Amazon Kindle all crowding the start screen. Dig in a bit more and you'll find some truely useful extras, like Skype, Acer Clear.fi (for networked media sharing), and Dragon Assistant (a voice recognition and dictation app). While the appeal of individual apps will vary by personal preference and usage patterns, it's clear that Acer has made an effort to be sure that there is plenty to do with the Aspire R7 right out of the box. Acer also covers the Aspire R7 with a one-year warranty.

Performance
Acer Aspire R7-571-6858 The Acer Aspire R7 is equipped with a 1.8GHz Intel Core i5-3337U processor paired with 6GB of RAM. It's the same processor seen in the Sony VAIO T15 Touch (SVT15112CXS), and actually did better in Cinebench, scoring 2.43 points to the Sony T15 Touch's 2.28, but the overall performance scores were very different. In PCMark 7 the Aspire R7 scored 2,702 points, falling behind every other 15-inch laptop with touch?the Sony T15 Touch scored 4,112 points in the same test, and the Editors' Choice Asus VivoBook S400CA-UH51 scored 3,013.

Acer Aspire R7-571-6858

The Aspire R7 planted itself firmly in the middle of the pack during multimedia tests, finishing in Handbrake in 1 minute 33 seconds and Photoshop in 5:43. By comparison, the Dell Inspiron 15z (I15Z-4801SLV) (1:33 Handbrake, 4:51 Photoshop) and the Sony VAIO T15 Touch (1:25 Handbrake, 5:21 Photoshop) both offer better performance with similar hardware. Though the use of Intel's integrated graphics solution isn't sufficient for high end gaming, a 3DMark score of 1,203 points (at Entry settings) indicate that it will do just fine handling Web browsing and video. Given the unusual design and layout of the Aspire R7, media consumption may be one of its best uses.

And while raw performance may not put the Acer Aspire R7 at the top of anyone's must-have list, it did eke out a bit more battery life than competitors, lasting 5 hours 41 minutes in our battery rundown test, outlasting the competition by nearly an hour or more.

Conclusion
In the end, however, the Acer Aspire R7 is a high-flying concept brought low by reality. While the design is daring and innovative, even among the many experimental designs being tried with convertible and touch-centric laptops, the end user experience shows it to be deeply flawed. With a swapped keyboard and trackpad layout that proves cumbersome, a floating touch screen display that adds little, and a bulky design that reduces portability, the Aspire R7 is more of a weird-looking proof of concept than a marketable product, and the middling to mediocre performance just cements it further as a product that may look cool on the shelf, but isn't the one shoppers should spend their money on.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/v19S-vp7Ags/0,2817,2420714,00.asp

hanley ramirez Christian Bale visits victims Christian Bale Sherman Hemsley Olympics Opening Ceremony Katherine Jackson Olympics Opening Ceremony Time

Why Won?t the FBI Tell the Public About its Drone Program?

Why Won?t the FBI Tell the Public About its Drone Program?

Today we?re publishing?for the first time?the FBI?s drone licenses and supporting records for the last several years. Unfortunately, to say that the FBI has been less than forthcoming with these records would be a gross understatement.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/_utLCaAyZIU/why-won-t-the-fbi-tell-the-public-about-its-drone-progr-529095768

lindzi cox bachelor finale courtney robertson ben flajnik hunger games premiere red meat bachelor ben

Friday, June 21, 2013

NSA leaker charged with espionage, theft

WASHINGTON (AP) ? The Justice Department has charged former National Security Agency contractor Edward Snowden with espionage and theft of government property in the NSA surveillance case.

Snowden, believed to be holed up in Hong Kong, has admitted providing information to the news media about two highly classified NSA surveillance programs.

A one-page criminal complaint unsealed Friday in federal court in Alexandria, Va., says Snowden engaged in unauthorized communication of national defense information and willful communication of classified communications intelligence information. Both are charges under the Espionage Act. Snowden also is charged with theft of government property. All three crimes carry a maximum 10-year prison penalty.

The federal court in the Eastern District of Virginia where the complaint was filed is headquarters for Snowden's former employer, government contractor Booz Allen Hamilton.

The complaint is dated June 14, five days after Snowden's name first surfaced as the leaker of information about the two programs in which the NSA gathered telephone and Internet records to ferret out terror plots.

The complaint could become an integral part of a U.S. government effort to have Snowden extradited from Hong Kong, a process that could turn into a prolonged legal battle. Snowden could contest extradition on grounds of political persecution. In general, the extradition agreement between the U.S. and Hong Kong excepts political offenses from the obligation to turn over a person.

It was unclear late Friday whether the U.S. had made an extradition request. Hong Kong had no immediate reaction to word of the charges against Snowden.

The Espionage Act arguably is a political offense. The Obama administration has now used the act in eight criminal cases in an unprecedented effort to stem leaks. In one of them, Army Pfc. Bradley Manning acknowledged he sent more than 700,000 battlefield reports, diplomatic cables and other materials to the anti-secrecy website WikiLeaks. His military trial is underway.

Sen. Bill Nelson, D-Fla., a member of the Senate Armed Services Committee, welcomed the charges against Snowden. "I've always thought this was a treasonous act," he said in a statement. "I hope Hong Kong's government will take him into custody and extradite him to the U.S."

Michael di Pretoro, a retired 30-year veteran with the FBI who served from 1990 to 1994 as the legal liaison officer at the American consulate in Hong Kong, said "relations between U.S. and Hong Kong law enforcement personnel are historically quite good."

"In my time, I felt the degree of cooperation was outstanding to the extent that I almost felt I was in an FBI field office," said di Pretoro.

The U.S. and Hong Kong have a standing agreement on the surrender of fugitives. However, Snowden's appeal rights could drag out any extradition proceeding.

The success or failure of any extradition proceeding depends on what the suspect is charged with under U.S. law and how it corresponds to Hong Kong law under the treaty. In order for Hong Kong officials to honor the extradition request, they have to have some applicable statute under their law that corresponds with a violation of U.S. law.

In Iceland, a business executive said Friday that a private plane was on standby to transport Snowden from Hong Kong to Iceland, although Iceland's government says it has not received an asylum request from Snowden.

Business executive Olafur Vignir Sigurvinsson said he has been in contact with someone representing Snowden and has not spoken to the American himself. Private donations are being collected to pay for the flight, he said.

"There are a number of people that are interested in freedom of speech and recognize the importance of knowing who is spying on us," Sigurvinsson said. "We are people that care about privacy."

Disclosure of the criminal complaint came as President Barack Obama held his first meeting with a privacy and civil liberties board as his intelligence chief sought ways to help Americans understand more about sweeping government surveillance efforts exposed by Snowden.

The five members of the little-known Privacy and Civil Liberties Oversight Board met with Obama for an hour in the White House Situation Room, questioning the president on the two NSA programs that have stoked controversy.

One program collects billions of U.S. phone records. The second gathers audio, video, email, photographic and Internet search usage of foreign nationals overseas, and probably some Americans in the process, who use major providers such as Microsoft, Google, Apple, and Yahoo.

___

Associated Press writer Jenna Gottlieb in Reykjavik, Iceland, contributed to this report.

Source: http://news.yahoo.com/nsa-leaker-charged-espionage-theft-001952096.html

Mayweather Fight Mayweather Robert Guerrero may day 747 crash Kentucky Derby 2013 Barcelona

Mt.Gox Bitcoin exchange freezes US dollar withdrawls for two weeks

MtGox Bitcoin exchange freezes US dollar withdrawls for two weeks

It's easy to see that the Bitcoin market is under stress when there's rising overall activity and tighter oversight. However, it's now so hectic that the Mt. Gox exchange has trouble fulfilling even basic transactions -- and the institution is freezing US dollar withdrawals for two weeks to keep things in check. Mt. Gox's team will use the downtime to upgrade its trading system and (hopefully) address the heavy workload. Deposits and transfers in American currency should still be good to go. Let's just hope that Mt. Gox manages smoother transitions in the future -- after all, not everyone can afford to leave their money in limbo during a tech refresh.

Filed under:

Comments

Via: Ars Technica

Source: Mt. Gox

Source: http://www.engadget.com/2013/06/20/mt-gox-bitcoin-exchange-freezes-us-dollar-withdrawls/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

jennifer hudson jennifer garner jennifer garner daytona 500 national margarita day Ronda Rousey Cecil Hotel

Mark-Paul Gosselaar Jokes: I ?Slave Away? to Afford a Nanny

"I don't raise [my daughters]," Meyer jokes, later adding, "I have a staff!"

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/7R80KFjsCvw/

Black Forest fire PS4 vs Xbox One ABC Family The Division the Pirate Bay chicago weather weather chicago

Thursday, June 20, 2013

Government leads new GM crops push

GM crops are probably safer than conventional plants, according to the Environment Secretary.

Making the strongest call yet for the adoption of the technology, Mr Paterson told the BBC that that GM has significant benefits for farmers, consumers and the environment.

He said the next generation of GM crops offers the "most wonderful opportunities to improve human health."

But green groups say this new push is dangerous and misguided.

The environment secretary has never made a secret of his support for GM technology. Speaking to the BBC ahead of a major speech in favour of GM, Mr Paterson said it was being adopted by the rest of the world and the UK and Europe risked being left behind.

He dismissed criticisms that GM could pose problems to human health.

"The use of more precise technology and the greater regulatory scrutiny probably make GMOs even safer than than conventional plants and food," he said.

"The EU chief scientist Anne Glover has said it pretty bluntly - there is no substantiated case of any adverse impact on human health on animal health or on environmental health."

Persuade the public

Mr Paterson said that GM offers benefits not just to UK consumers and farmers but holds a great deal of promise especially in the developing world. He cited the example of Golden Rice, a GM variety that has been modified to have increased levels of vitamin A.

Continue reading the main story

Global GM

Last year about 170 million hectares of GM crops were cultivated in 28 countries. Proponents argue that about half of the GM crops grown worldwide are produced by resource poor farmers. Apart from the US, the world's leading growers are Brazil, Argentina, Canada and India.

This helps prevent blindness in young children especially in deprived environments. But even though the rice was developed in 1999, it has yet to be grown commercially.

"Every attempt to deploy has been thwarted and in that time seven million children have gone blind or died," said Mr Paterson.

In his speech on Thursday morning at Rothamsted Research in Harpenden, Mr Paterson argued that the government, along with industry and the scientific community "owe a duty to the British public to reassure them GM is a safe, proven and beneficial innovation".

The European Union has been deadlocked on GM for a number of years. Only two crops have been approved for commercial growing - another seven are awaiting the green light.

In the speech, Mr Paterson suggested that member states which are open to the safe use of GM crops should not be prevented from moving forward with the technology.

"We need evidence-based regulation and decision-making in the EU. Consumers need accurate information in order to make informed choices. The market should then decide if a GM product is viable," he said.

"Farmers are also consumers but right now that market is not functioning and they are being denied choice. That's why I want to explore ways of getting the EU system working, as this will encourage further investment and innovation."

But critics have been quick to condemn Mr Paterson's view that GM is a "safe, proven and beneficial innovation".

Soil Association policy director Peter Melchett said that GM would make it harder, not easier, to feed the world.

"The British Government constantly claim that GM crops are just one tool in the toolbox for the future of farming. In fact GM is the cuckoo in the nest. It drives out and destroys the systems that international scientists agree we need to feed the world.

"We need farming that helps poorer African and Asian farmers produce food, not farming that helps Bayer, Syngenta and Monsanto produce profits," he added.

Kirtana Chandrasekaran, from Friends of the Earth, said: "We have loads of other types of farming science that are delivering, that are, through conventional breeding, giving us drought tolerant crops.

"They are starved of funding... We are continuing to flog GM when it's not delivering what we need."

Mr Paterson's stance was backed by a number of scientists, including Professor Dale Sanders, the Director of the John Innes Centre in Norwich. He wants to see a greater focus on solving global problems such as malnutrition rather than arguments about one technology or another.

Continue reading the main story

EU spud spat

Only two commercial GM products have so far been licensed, and neither of them was for human consumption.

One was a type of potato called Amflora developed by German chemical firm BASF. It had been modified to produce more of a type of starch useful for industrial processes.

But in January this year, BASF announced it was withdrawing the product and ending development of all its GM potato varieties.

The commercially grown GM is a type of maize made by Monsanto. Modified to make it resistant to pests, it is mainly grown in Spain for animal feed.

"Evaluation of potential scientific solutions to agriculture should be evidence-based," he said.

"The overwhelming global conclusion regarding the deployment of GM technologies in the field is that the risks associated with the technologies are infinitesimally small."

Mr Paterson's speech comes in the same week that the National Farmers Union warned that the UK's wheat crop could be 30% smaller than last year because of extreme weather.

The environment secretary said that GM could "combat the damaging effects of unpredictable weather and disease on crops".

The technology has "the potential to reduce fertiliser and chemical use, improve the efficiency of agricultural production and reduce post-harvest losses. If we use cultivated land more efficiently, we could free up space for biodiversity, nature and wilderness."

At present there are no commercial GM crops grown in the UK although cattle, sheep and pigs are often fed on imported GM. There is only one active GM trial of wheat that has been modified to deter aphids.

Follow Matt on Twitter.

Source: http://www.bbc.co.uk/news/science-environment-22967571#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

Adam Lanza cnbc dexter dexter Sandy Hook Victims columbine Newton

Saturday, April 27, 2013

Stock Downgrades: Anheuser-Busch Set For Friday Night Hangover ...

Yesterday?s?Dow?(^DJI) increase of only 24.50 points may not have been anything on the excitement of exactly six years earlier, but it?ll do for now.
?
Strange bedfellows dominated the day, what with?Jimmy Carter gushing over George Bush?and the Wall Street Journal turning over its editorial page?to a New York Times (NYT) journalist who did jail time. (Such a selfless gesture from right wing to left, and on?Pay It Forward Day?no less, sent shares of the Old Grey Lady surging some 5.00%.)
?
Elsewhere Kentucky Fried Chicken owner?Yum Brands?(YUM), which jumped 7.10% on Wednesday and scored an?analyst upgrade 24 hours later, tumbled 2.11% after it became apparent that?Colonel Sanders? favorite food was actually?White Castle.
?
Today in economics, consensus says April?s University of Michigan consumer sentiment survey will show an improvement at 9:55 a.m. Eastern. Peak earnings week concludes with announcements expected out of?Alcatel-Lucent?(ALU),?Burger King (BKW), Chevron (CVX), DR Horton (DHI),?Goodyear Tire?(GT),?Honda Motor?(HMC),?LyondellBasell (LYB), Total SA?(TOT),?Tyco International (TYC),?VF Corporation (VFC), and?WellPoint?(WLP).
?
Alkermes?(ALKS): The stock is downgraded to Underperform from Neutral at Bank of America-Merrill Lynch.
?
AmerisourceBergen?(ABC): Shares are now Neutral from Outperform at Robert W. Baird, which trims its target to $57 from $59 after a recent run to record highs.
?
Anheuser-Busch?(NYSE:BUD): The brewing behemoth is slashed to Conviction Sell ? surely the ultimate ignominy ? from merely Sell at Goldman Sachs. Shares are lower in today?s pre-market trading as a result.
?
Baidu Inc.?(BIDU): Shares in the Chinese Internet outfit, imploding 8% before the opening bell, get downgraded to Hold from Buy at Brean Capital.
?
Beneficial Mutual Bancorp?(BNCL): The name is now Neutral from Buy at Sterne Agee.
?
Carpenter Technology?(CRS): CRS gets cut to Neutral from Overweight at JPMorgan.
?
Duke Realty?(DRE): The stock is moved to Market Perform from Outperform by BMO Capital.
?
Embraer?(ERJ): Shares are slashed to Sell from Neutral at Citigroup.
?
Exxon Mobil?(XOM): The oil giant and key?Dow?(^DJI) component is now Neutral from Buy at ISI Group.
?
F5 Networks?(FFIV): Shares are downgraded to Perform from Outperform at FBR Capital, which notes competitive threats from Intel (INTC) among others.
?
Hancock Holding?(HBHC): The stock is now Hold from Buy with Wunderlich.
?
ITT Educational Services?(ESI): The stock is downgraded to Sell from Neutral at Compass Point.
?
KLA-Tencor?(KLAC): KLAC gets cut to Outperform from Buy at CLSA.
?
Raymond James Financial?(RJF): Citigroup reduces its recommendation on RJF to Neutral from Buy.
?
Windstream?(WIN): The equity is now Neutral from Buy at Bank of America-Merrill.

(See also: New Stock Coverage: TherapeuticsMD Is Just What the Doctor Ordered and Stock Upgrades: Don?t Throw Bebe Out With the Bath Water.)

No positions in stocks mentioned.

The information on this website solely reflects the analysis of or opinion about the performance of securities and financial markets by the writers whose articles appear on the site. The views expressed by the writers are not necessarily the views of Minyanville Media, Inc. or members of its management. Nothing contained on the website is intended to constitute a recommendation or advice addressed to an individual investor or category of investors to purchase, sell or hold any security, or to take any action with respect to the prospective movement of the securities markets or to solicit the purchase or sale of any security. Any investment decisions must be made by the reader either individually or in consultation with his or her investment professional. Minyanville writers and staff may trade or hold positions in securities that are discussed in articles appearing on the website. Writers of articles are required to disclose whether they have a position in any stock or fund discussed in an article, but are not permitted to disclose the size or direction of the position. Nothing on this website is intended to solicit business of any kind for a writer's business or fund. Minyanville management and staff as well as contributing writers will not respond to emails or other communications requesting investment advice.

Copyright 2011 Minyanville Media, Inc. All Rights Reserved.

Source: http://www.minyanville.com/trading-and-investing/stocks/articles/Stock-Downgrades253A-Anheuser-Busch-Set-For/4/26/2013/id/49500

clive davis nba trade thomas robinson nba trades ign Xbox 720 HTC One

Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong

Apr. 26, 2013 ? A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of Prof. Robert Ros, and the lead author of a paper reporting on the topic.

Metastasis is a critical step in the progression of cancer. It is when the cancer spreads from one organ or part to another. While much is known about metastasis, it remains an incomplete understanding of the physical biology of the transition.

To get a better understanding of metastasis, more than 95 graduate students, post docs and professors in a variety of laboratories across the U.S. subjected two cell lines to a battery of high-tech tests and measurements. Their results were published April 26, 2013 in Scientific Reports.

The researchers performed coordinated molecular and biophysical studies of non-malignant and metastatic breast cell lines to learn more about what happens to a cell when it transitions to a metastatic state.

Each laboratory is part of the National Cancer Institute's Physical Sciences Oncology Center (PSOC), a network of 12 centers devoted to understanding the physical sciences of cancer. ASU's center, the Center for the Convergence of Physical Science and Cancer Biology, is led by Prof. Paul Davies.

Each PS-OC was supplied with identical cell lines and common reagents, and considerable effort was made to ensure that all the conditions were standardized and documented at regular intervals. Staunton said the ASU group made three contributions to the study.

Other ASU researchers involved in the project and co-authors on the paper are: Alexander Fuhrmann, Vivek Nandakumar, Laimonas Kelbauskas, Patti Senechal, Courtney Hemphill, Roger H. Johnson and Deirdre Meldrum.

"We compared the stiffness of normal breast cells and highly metastatic breast cancer cells, and found the cancer cells to be significantly more 'squishy' or deformable," Staunton said. "This makes sense because in order for a cell to metastasize, it has to squeeze through tight passages in the lymphatics and microvasculature, so being squishy helps cancer cells spread through the body."

"We also looked at the morphology of their nuclei," he added. "The cancer cell nuclei were found to have a characteristic 'crushed beach-ball' shape that might correspond to the abnormal chromosomal rearrangements associated with cancer."

"Finally, we took individual cells, put each one in an airtight chamber, and measured how much oxygen they consumed," Staunton said. "This tells us about their metabolism. We found the cancer cells use less oxygen, relying more on glycolysis, kind of like what bacteria and yeast do."

Taken together, researchers at the 12 PSOC's used some 20 distinct techniques, including atomic force microscopy, ballistic intracellular nano-rheology, cell surface receptor expression levels, differential interference contrast microscopy, micro-patterning and extracellular matrix secretion, and traction force microscopy.

The work has enabled a comprehensive cataloging and comparison of the physical characteristics of non-malignant and metastatic cells, and the molecular signatures associated with those characteristics. This made it possible to identify unique relationships between observations, Staunton said.

"We were surprised that even though the cancer cells are softer, they are able to exert more contractile forces on the fibers surrounding them -- which was determined at the Cornell University PSOC by a method called traction force microscopy. This pair of characteristics is somewhat contradictory from a purely physical perspective, but it makes sense for a cancer cell, since both traits improve their chances of metastasizing. Understanding why is still an active area of research," explained Staunton, who is working towards his doctorate in physics.

"Another interesting finding was that a protein called CD44, which doubles as a cancer stem cell marker and as a molecule that helps the cell stick to certain fibers in the extracellular matrix, is equally abundant in the normal and cancer cells. But in the cancer cells the proteins don't make it to the cell surface," he added.

"For some reason they stay inside the cytoplasm, so the cancer cells are not as sticky," added Staunton whose hometown is Buffalo, N.Y. "This is another trait that contributes to their ability to spread through the body."

The PSOC network went to great lengths to have all of the studies performed under comparable conditions. While the cell lines studied are well understood, part of the effort for the network was to prove they could consistently coordinate the research.

Staunton, who has been involved in ASU's center since its inception, says the experience has helped his growth as a researcher.

"It is the perfect habitat for budding scientists and for transdisciplinary collaborations," he said.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Arizona State University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David B. Agus, Jenolyn F. Alexander, Wadih Arap, Shashanka Ashili, Joseph E. Aslan, Robert H. Austin, Vadim Backman, Kelly J. Bethel, Richard Bonneau, Wei-Chiang Chen, Chira Chen-Tanyolac, Nathan C. Choi, Steven A. Curley, Matthew Dallas, Dhwanil Damania, Paul C. W. Davies, Paolo Decuzzi, Laura Dickinson, Luis Estevez-Salmeron, Veronica Estrella, Mauro Ferrari, Claudia Fischbach, Jasmine Foo, Stephanie I. Fraley, Christian Frantz, Alexander Fuhrmann, Philippe Gascard, Robert A. Gatenby, Yue Geng, Sharon Gerecht, Robert J. Gillies, Biana Godin, William M. Grady, Alex Greenfield, Courtney Hemphill, Barbara L. Hempstead, Abigail Hielscher, W. Daniel Hillis, Eric C. Holland, Arig Ibrahim-Hashim, Tyler Jacks, Roger H. Johnson, Ahyoung Joo, Jonathan E. Katz, Laimonas Kelbauskas, Carl Kesselman, Michael R. King, Konstantinos Konstantopoulos, Casey M. Kraning-Rush, Peter Kuhn, Kevin Kung, Brian Kwee, Johnathon N. Lakins, Guillaume Lambert, David Liao, Jonathan D. Licht, Jan T. Liphardt, Liyu Liu, Mark C. Lloyd, Anna Lyubimova, Parag Mallick, John Marko, Owen J. T. McCarty, Deirdre R. Meldrum, Franziska Michor, Shannon M. Mumenthaler, Vivek Nandakumar, Thomas V. O?Halloran, Steve Oh, Renata Pasqualini, Matthew J. Paszek, Kevin G. Philips, Christopher S. Poultney, Kuldeepsinh Rana, Cynthia A. Reinhart-King, Robert Ros, Gregg L. Semenza, Patti Senechal, Michael L. Shuler, Srimeenakshi Srinivasan, Jack R. Staunton, Yolanda Stypula, Hariharan Subramanian, Thea D. Tlsty, Garth W. Tormoen, Yiider Tseng, Alexander van Oudenaarden, Scott S. Verbridge, Jenny C. Wan, Valerie M. Weaver, Jonathan Widom, Christine Will, Denis Wirtz, Jonathan Wojtkowiak, Pei-Hsun Wu. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports, 2013; 3 DOI: 10.1038/srep01449

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/bVQjS3PQ97M/130426135034.htm

Joey Kovar Expendables 2 Pussy Riot National Hurricane Center Zeek Rewards vanessa bryant vanessa bryant

Clues to making vaccine for infant respiratory illness

Apr. 25, 2013 ? An atomic-level snapshot of a respiratory syncytial virus (RSV) protein bound to a human antibody represents a leap toward developing a vaccine for a common -- and sometimes very serious -- childhood disease. The findings, by scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, define the vulnerable shape of a critical RSV component called the fusion glycoprotein.

The NIAID scientists determined the fusion glycoprotein's shape as it appears before its interaction with human cells. It is this pre-fusion shape that is most vulnerable to neutralizing antibodies. Progress toward an RSV vaccine has been stalled in part because researchers did not previously know about a highly vulnerable site at the tip of the pre-fusion form of the fusion glycoprotein. Now that the structure has been solved and the site of antibody vulnerability revealed, scientists can use the new structural information to design vaccines capable of eliciting potent antibodies aimed at the target on top of the pre-fusion state of the glycoprotein.

Almost everyone is infected with RSV before turning three years of age. Most children recover quickly from such symptoms as sneezing, runny nose and cough, but the virus is a leading cause of hospitalization in children under age one. In the United States each year between 75,000 and 125,000 children in this age group are hospitalized with RSV infection. Globally, RSV infection accounts for nearly 7percent of deaths among children between the age of one month and one year. The only drug available to prevent severe RSV illness is a monoclonal antibody, palivizumab, which binds to the RSV fusion glycoprotein.

In their study, the NIAID researchers showed how three antibodies that potently neutralize RSV all bind to the newly revealed site on the fusion glycoprotein of RSV. Thus, in addition to new clues for vaccine developers, the NIAID findings also provide a structural basis for how these antibodies neutralize RSV. This insight could accelerate development of these antibodies into therapies to treat or prevent severe RSV disease in very young infants, who are the most vulnerable to serious illness.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by NIH/National Institute of Allergy and Infectious Diseases, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Jason S. McLellan, Man Chen, Sherman Leung, Kevin W. Graepel, Xiulian Du, Yongping Yang, Tongqing Zhou, Ulrich Baxa, Etsuko Yasuda, Tim Beaumont, Azad Kumar, Kayvon Modjarrad, Zizheng Zheng, Min Zhao, Ningshao Xia, Peter D. Kwong, and Barney S. Graham. Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody. Science, 25 April 2013 DOI: 10.1126/science.1234914

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/4ZGhrONTNNI/130425142434.htm

completely wrong stacey dash christopher columbus columbus day columbus day Stacy Dash Amber Tamblyn

Living with Google Glass, Day One: the reveal

DNP Living with Google Glass, Day One the reveal

In a loft atop Chelsea Market, Google is doing something special. Here, lucky Explorers will get their first taste of Project Glass. Yes, Google's latest X project (that we know about, at least) has finally made its way to the East Coast en masse. More importantly, it's also made its way to my face. A full Engadget review of the headset is most certainly on the way, but this is the sort of thing that will take some time to evaluate. You can quite quickly size up the next iteration of a great smartphone. Evaluating a wholly new product category to see how it fits into your life? That takes a little longer, dear readers.

I plan to spend a little while living with Glass in a variety of ways, some exciting and many less so, with the goal of getting comfortable with the thing -- or uncomfortable, if that's how it turns out. Given how many of you are excited to read about Google's new wearable, we wanted to let you come along for the ride. After all, isn't sharing an experience what Glass is really all about? Join me for my very first impressions after picking up my headset and some sample footage of the trip home.

Filed under: ,

Comments

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/u2bUDZk_glM/

metta world peace suspension apple earnings report john l smith apple earnings the glass castle jennifer hudson trial north korea threat

Google Brings Its New And Improved File Viewer For MS Office Documents To Chrome Beta

office_viewer_chrome_2If you regularly need to open Microsoft Office documents in the browser, Google now offers you a new Chrome extension that renders Word, Excel and PowerPoint files directly in the browser. Currently, these documents open in a Drive-based viewer, but after you install the new Chrome Office Viewer (which is officially still in beta), these documents will open directly in the browser. Until now, this feature was limited to Chromebooks, but now it’s also available for Chrome on Windows and Mac. You do need to run Chrome Beta, however, as it’s not available for the stable release channel of Chrome just yet. The advantage of this new plug-in (which weighs in at over 20 megabytes), Google says, is that it ensures that you are protected from malware because the files open in a specialized sandbox “to impede attackers who use compromised Office files to try to steal private information or monitor your activities.” While Google doesn’t say so in today’s announcement, chances are this new feature is at least partially powered by the technology it acquired when it bought Quickoffice last year. When Google launched the Pixel Chromebook in February, it also said it would port Quickoffice to Chrome, using its Native Client technology. Those three months are almost over, so we’ll likely see a bit more from Google with regard to Office documents in the browser.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/2UTTJYJG7Zs/

lindsay lohan on snl real housewives of disney awakenings phantom of the opera agoraphobia andrew lloyd webber obscura

Senate deal reached on FAA furlough bill

WASHINGTON (AP) ? With flight delays mounting, the Senate has passed legislation to end air traffic controller furloughs blamed for inconveniencing large numbers of travelers.

Approval came without dissent, and long after many senators had left the Capitol for a weeklong vacation.

A House vote is expected as early as Friday.

Under the measure, the Federal Aviation Administration would gain authority to transfer up to $253 million from accounts that are flush into other programs, to "prevent reduced operations and staffing" through the Sept. 30 end of the fiscal year.

Officials said that would likely be enough to restore full staffing for the furloughed controllers, as well as prevent the closure of small airport towers.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-04-25-FAA-Furloughs/id-afd44c5716c74d678626a265bc1f035b

big brother iOS 6 bank of america Yunel Escobar Eye Black Cruel Summer Endeavor shaun white

Friday, April 19, 2013

Boston blast investigators identify a face



>>> we will find out and we will hold accountable and bring to justice whoever is responsible. but this investigation is now not even 48 hours old and it is important that we maintain the integrity of the investigation.

>> today, the fbi first postponed and then canceled their regular briefing on the investigation into the boston marathon bombing. authorities told ncbc news that authorities have a face but not the name of someone seen on camera. they just have the face. someone dropping a black bag near the second blast site. an official says investigators are zeroing in on some people. joining me now is nbc news national investigative correspondent michael isikoff and agent james calf nau. how did the news media get out of control on this, some of the other networks saying they had an arrest and then how did that in any way possibly lead to the canceling of the regular briefing?

>> we don't know for sure. and it's too bad because it would have been good to clear up what's become a confusing situation but my sense is, some investigators got pretty excited about these surveillance photos, that they were able to identify somebody who they thought had left off a bag at the bomb site that could have been the bomb. they were helped very much by the footage they got in from the camera at the lord & taylor department store , a few hundred yards down the road here. and that led to a lot of excitement and hopes that there had been a major breakthrough. it's not clear how big of a breakthrough it is. clearly it's progress. clearly they've got something to work with. but i'm -- we're reporting tonight that they've distributed -- the fbi is distributing a photo image of the individual to other federal law enforcement agencies asking for them to help in helping to identify this individual. it's a pretty good indication they don't know at this moment who that is. and so this could still be yet quite an arduous task without a name who they are looking for. they don't know who they are looking for and beyond that, they don't know that that person is necessarily connected to the bombing. they know that they've got surveillance photo that is suggestive and raises questions and they want answers. but we're still pretty far off from getting a real breakthrough in this case.

>> james cavanaugh , an asset that the fbi and police do not have is the ability to trace gunpowder. why do they not have that ability now?

>> that was blocked in the '70s. these were little taggants, the size of a period on a piece of paper. i was around at the time, we trained with them, they were magnetic and they would glow in the dark . we would go out with magnets, special gloves, black lights , and we could actually recover these taggants after a bomb detonated and be able to tell us the date shift code, which is basically the lot and serial number of a batch of dynamite. we were very excited about it. we sent some of those explosives into the field, a homicide case was solved in the baltimore division with it but eventually when it got to the hill, gun lobby got involved, basically said, you know, if you let the atf tag explosives, next they are going to tag the powder and then road den drons and whatever. it hurt many bombing cases which is atf is particularly interested in solving 40 years ago and through today.

>> and james , where do you think this investigation would be tonight were it not for the nra's blocking that particular investigative tool?

>> well, in theory, lawrence, it could have given us a lot number. in theory, that's possible. you know, when you're working on a difficult case like this as mike described, every little bit of information can help you build the case. but you just had the governor on and i just want to i sa, this case from afar was being well run. this task force was tight, despite what happened today in the media, this task force is great. you can see the way it's been running. i've been involved in many of these cases. the agencies, boston police , boston police bomb squad , detective bureau right on through the state police , immigration, u.s. attorney , and i've worked with governor patrick. he flew to alabama and worked with me on the church fires. he's a good leader. they are doing a great job and they are going to break the case.

>> james , do you have any insight as to why this briefing would have been canceled today?

>> i think the commanders are probably at a decision point on whether or not they are going to further release the images. meek talked about it and he's exactly right. you know, you have an image, it could be very significant to identify a person or not. let me give you an example. in the eric rudolph case, we had a photograph of eric rudolph with the alice pack , with a backpack, with a bomb in it at olympic park but the photograph was so distant, we could hardly make him out. we used to call them in the command post , blob man, because we could see him threw but couldn't make out the features. we had that image for years but were never able to get an identification from it. so the clarity of the video, is the face available, is the clothes readily recognizable. the commanders are trying to make all of those decisions carefully. and i would say this. i try to release it in a tight circle to see if i can get something first and then start making the decision, i wouldn't want to start holding that too long if i thought i could get to the identity of the guy or perpetrators by releasing to the public. because the main thing is to catch these bombers before they strike again.

>> michael isikoff , it seems that the next fbi briefing will, for some number of minutes anyway, be bogged down in the procedural question of why did you cancel the last briefing. and up until now it's been a flawlessly run system.

>> well, look, they've also got to figure out exactly what they are going to say and exactly how much they are going to release. they are going to be bombarded with questions about what they know about the potential persons of interests. i hesitate to call them suspects. they haven't called them suspects yet. but how much they know, how much they want to release, do they want to solace sit help from the public in identifying who these people are? my sense is they are not there yet. that's why they are showing the photos that i'm told was being distributed tonight involves a white man with a baseball cap about six feet tall or more. now, the first blush is, do you have anything that looks like this guy? do you know anything about this person? if they don't get something fairly quickly, i think they may well go to the public and we may well be seeing this photo asking the public, have you ever seen this person?

>> michael isikoff , james calf nau, thank you both for joining me tonight.

>> thanks, lawrence.

>>> coming up, rand paul's insults to the parents of the children killed at sandy hook elementary school . you will see president obama 's response to that in his own angry words. and the mother of the 9-year-old girl who was killed in the shooting that took down gabby giffords will join me and she will also respond to what rand paul

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2ada8987/l/0Lvideo0Bmsnbc0Bmsn0N0Cid0C51578128/story01.htm

awkward Girls Love Beyonce gun control Patton Oswalt Outside Lands washington post Family Guy Boston Marathon